| Characteristic | Details |
|---|---|
| Generic Names | Nifedipine |
| Dosage Forms | 10 mg, 20 mg, 30 mg |
| Administration Route | Oral |
| Prescription Status | Prescription Only |
| More Information on Adalat | |
Adalat Generic Names
Nifedipine forms the core component of Adalat. It belongs to the class of medications known as calcium channel blockers. This pharmacological group manages hypertension and angina. By relaxing blood vessels, it enhances blood flow and reduces blood pressure.
Nifedipine is available in several formulations. Immediate-release tablets are common. Sustained-release capsules and extended-release tablets are also prevalent. The range of formulations offers flexibility in dosage. Tailored treatment regimens are thus achievable.
Adalat’s distinct formulations address varying therapeutic needs. Patients experience reduced cardiovascular strain. This results in lower instances of chest pain and hypertension.
Mechanism of Action
Nifedipine operates by inhibiting calcium ions from entering vascular smooth muscle and myocardial cells. Calcium ions play a pivotal role in the contraction of these muscle tissues. Blocking them reduces contractility, thus promoting vasodilation.
Vasodilation reduces peripheral resistance and decreases arterial pressure. In angina patients, this leads to decreased cardiac workload. As a result, oxygen demand lessens, alleviating chest pain. This action underpins Nifedipine’s efficacy in treating chronic stable angina and variant angina.
The mechanism of Nifedipine aligns with its therapeutic use. It directly addresses key symptoms of cardiovascular diseases.
Adalat Contraindications
Adalat should not be used in patients with known hypersensitivity to nifedipine. Those with cardiogenic shock should also avoid it. Patients with significant aortic stenosis fall under this contraindication as well.
It is contraindicated during pregnancy unless the benefit justifies the potential risk. Lactating mothers should also refrain from using Adalat. The drug might pass into breast milk and affect the infant.
Comprehensive patient history is essential before prescribing Adalat. Understanding the full medical context ensures safer use of this medication.
Cautions with Other Medicines
Patients taking Adalat should exercise caution when combining it with other drugs. Simultaneous use of beta-blockers might intensify the hypotensive effect. This could potentially lead to severe cardiovascular complications.
Grapefruit juice alters the metabolism of nifedipine. This increases the risk of adverse effects. Patients should avoid consuming grapefruit products while on this medication.
Co-administration with drugs inducing cytochrome P450 3A4, like rifampicin, may decrease nifedipine levels. This may reduce its therapeutic effectiveness.
Adalat Signs and Symptoms of Overdose
An overdose of Adalat can cause significant symptoms. Acute hypotension is common, leading to dizziness and fainting. In severe cases, this could result in cardiovascular collapse.
Bradycardia or tachycardia may occur. This can disrupt normal heart rhythm, posing serious health risks. Confusion, lethargy, and metabolic acidosis might manifest.
Immediate medical attention is necessary in suspected overdose cases. Supportive treatment, including cardiovascular support, becomes critical. Activated charcoal may limit nifedipine absorption if administered quickly.
Is Non-prescription Adalat Available?
Adalat is not available as a non-prescription drug. Its use requires a thorough evaluation by a healthcare professional. Unsupervised intake could result in adverse health consequences.
The necessity for prescription stems from potential interactions and contraindications. Patients need monitoring to ensure optimal therapeutic outcomes and minimize risks.
Adalat remains a cornerstone in managing hypertension and angina. Its prescription status safeguards patients against improper use, maintaining its role in comprehensive cardiovascular care.
| Interaction | Effect |
|---|---|
| Beta-blockers | Increased risk of hypotension |
| Grapefruit Juice | Increases nifedipine levels |
| CYP3A4 Inducers | Reduced drug effectiveness |
Data source:
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